Tuesday, April 30, 2024

Publications

  • Doan TB, Cheung C, Clyne CD, Hilton HN, Eriksson N, Young MJ, Funder JW, Muscat GEO, Fuller PJ, Clarke CL, Graham JD (2020) A tumour suppressive relationship between mineralocorticoid and retinoic acid receptors activates a transcriptional program consistent with a reverse Warburg effect in breast cancer. Breast Cancer Res. 2020 Nov 4;22(1):122
  • Hilton HN, Patterson McDonald LJ, Santucci N, van der Bent FR, Silvestri A, Graham JD, Clarke CL (2019) BRCA1 attenuates progesterone effects on proliferation and NFkappaB activation in normal human mammary epithelial cells. J Mammary Gland Biol Neoplasia May 18.
  • Hilton HN, Clarke CL, Graham JD (2018) Estrogen and progesterone signalling in the normal breast and its implications for cancer development. (Review) Mol Cell Endocrinol. May 5;466:2-14  

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  • Hilton HN, Graham JD and Clarke CL (2015) Minireview: Progesterone regulation of proliferation in the normal human breast and in breast cancer: A tale of two scenarios? (Review) Mol Endocrinol. Sep;29(9):1230-42
  • Hilton HN and Clarke CL (2015) Impact of progesterone on stem/progenitor cells in the human breast. (Review) J Mammary Gland Biol Neoplasia. Jun;20(1-2):27-37
  • Clarke C, Dontu G, Hilton H, Meier-Abt F, Sartorius C (2015) Preface J Mammary Gland Biol Neoplasia. Jun;20(1-2):5-7
  • Mote PA, Gompel A, Howe C, Hilton HN, Sestak I, Cuzick J, Dowsett M, Hugol D, Forgez P, Byth K, Graham JD and Clarke CL (2015) Progesterone receptor A predominance is a discriminator of benefit from endocrine therapy in the ATAC trial. Breast Cancer Res Treat. Jun;151(2):309-18
  • Hilton HN, Doan TB, Graham JD, Oakes SR, Silvestri A, Santucci N, Kantimm S, Huschtscha LI, Ormandy CJ, Funder JW, Simpson ER, Kuczek ES, Leedman PJ, Tilley WD, Fuller PJ, Muscat GEO and Clarke CL (2014) Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease.Oncotarget Sep 30;5(18):8651-64.NormalHilton HN and Graham JD (2014) The molecular landscape of the normal human breast – defining normal. (Invited editorial) Breast Cancer Res. 16:102.
  • Hilton HN, Santucci N, Silvestri A,  Kantimm S, Huschtscha LI, Graham JD and Clarke CL (2014) Progesterone stimulates progenitor cells in normal human breast and breast cancer cells. Breast Cancer Res Treat. Feb;143(3):423-33.
  • Hilton HN, Kantimm S, Graham JD and Clarke CL (2013) Changed lineage composition is an early event in breast carcinogenesis. Histol Histopathol. Sep;28(9):1197-204
  • Hilton HN, Graham JD, Clarke CL. Progesterone receptor. Encyclopedia of Cancer Therapeutic Targets. Marshall, JL (Ed.) Published by Springer; 1st Edition (June 3, 2013; Book chapter).
  • Hilton HN, Graham JD, Kantimm S, Santucci N, Cloosterman D, Huschtscha LI, Mote PA and Clarke CL (2012). Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast. Mol Cell Endocrinol. Sep 25;361(1-2):19facs1-201.
  • Hilton HN, Graham JD and Clarke CL (2012). Estrogen and progestin stimulation of breast proliferation. Translational Endocrinology and Metabolism: The breast as a hormonal target organ (March 2012;3(1);17-44 Review).
  • Hilton HN, Kalyuga M, Cowley MJ, Alles MC, Lee HJ, Caldon CE, Blazek K, Kaplan W, Musgrove EA, Daly RJ, Naylor MJ, Graham JD, Clarke CL, Ormandy CJ. (2010) The antiproliferative effects of progestins in T47D breast cancer cells are tempered by progestin induction of the ETS transcription factor Elf5. Mol Endocrinol. Jul:24(7):1380-92.
  • Hilton HN, Stanford PM, Harris J, Oakes SR, Kaplan W, Daly RJ and Ormandy CJ. (2008) KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling. Biochim Biophys Acta. Mar;1783(3):383-93
  • Oakes SR, Naylor MJ, Asselin-Labat M-L, Blazek KD, Gardiner-Garden, M, Hilton HN, Kazlauskas M, Pritchard MA, Chodosh LA, Pfeffer PL, Lindeman GJ, Visvader JE and Ormandy CJ. (2008) The Ets transcription factor Elf5 specifies mammary alveolar cell fate. Genes Dev. Mar 1; 22(5)xxx
  • Oakes SR, Hilton HN, Ormandy CJ. (2006) Key stages in mammary gland development – The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium. (Review) Breast Cancer Res. Apr 25;8(2):207.
  • Harris J, Stanford PM, Sutherland K, Oakes SR, Naylor MJ, Robertson FG, Blazek KD, Kazlauskas M, Hilton HN, Wittlin S, Alexander WS, Lindeman GJ, Visvader JE, Ormandy CJ. (2006) Socs2 and Elf5 mediate prolactin-induced mammary gland development. Mol Endocrinol. May;20(5):1177-87
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